STABILITY TEST OF CLOVE FLOWER ESSENTIAL OIL OINTMENT (SYZIGIUM AROMATICUM L) WATER SOLUTION BASED IN PLASTIC AND GLASS PACKAGING
نویسندگان
چکیده
Cengkeh (Syzygium aromaticum L) merupakan salah satu tanaman herbal yang sering digunakan masyarakat karena kandungan utama minyak atsiri bunga cengkeh (Syzigium aromaticum) adalah eugenol memiliki khasiat sebagai antiinflamasi. Formulasi salep telah dilakukan dengan membuat sediaan dalam basis larut air (PEG). Salah persyaratan stabil. Penggunaannya secara tradisional memerlukan waktu penyiapan lama sehingga perlu formulasi lebih praktis dan stabil penyimpanan. Tujuan penelitian ini untuk mengetahui stabilitas (PEG) baik optimal. Minyak diformulasi bentuk kemasan tube plastik gelas. Evaluasi pada uji sifat fisika meliputi organoleptik, viskositas, pH, sentrifuga, freezer thaw Uji penyimpanan Climatic chamber kondisi suhu 40°C ± 2°C kelembaban 75% RH 5% selama 90 hari kemudian diuji ke-0, ke-7, ke-14, ke-30, ke-60 ke-90. Analisis data statistik menggunakan SPSS metode two way ANNOVA. Hasil menunjukkan bahwa pengemas dapat menurunkan viskositas pH. Kombinasi polietilen glikol 400 4000 membentuk formula optimum perbandingan 67% 28% rancangan formula.
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ژورنال
عنوان ژورنال: Jurnal Farmasimed
سال: 2022
ISSN: ['2655-0814']
DOI: https://doi.org/10.35451/jfm.v5i1.1254